What began in 2006 at AMT with the 2.7 µm C18 HALO® particle that proved the possibility for high efficiency separations with conventional HPLC’s has revolutionized the chromatography world! The innovation continues by forging a new path through manipulations of the particle morphology which has advanced the chromatographic separations in the biopharmaceutical and environmental industries. The timeline above represents AMT’s commitment to delivering innovative tools to enhance the separation resolution afforded by the column technology.
FIB – SEM image of first commercial HALO® particle with 2.7 µm total size consisting of a 1.7 µm solid silica core and a 0.5 µm shell.
Higher efficiencies (higher plate count (N), smaller plate height, (H)) for SPP columns are due to a combination of all three van Deemter A, B and C terms being smaller for SPP particles.
The original HALO® Fused-Core® columns are able to perform competitively versus sub-2 µm fully porous columns and substantially outperform 3 and 5 µm fully porous columns delivering the goal of increased performance without the consequence of high back pressures!
The challenge of improving the presentation of the sample to the detector is our focus. As the realization of SPP benefits became more mainstream, recognized at first by thought leaders and then more universally adopted, ongoing development of the particle morphology has been underway.
Advanced Materials Technology, founded in 2005, has been focused on one mission – Improving the presentation of the sample to the detector. Using our novel Fused-Core® particle design, we have challenged conventional wisdom and engineered innovative solutions for the separations community.
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